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doi: 10.1186/s12906-017-1915-9 257 PratheeshkumarPKuttanG

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It is currently in phase IIb trial aiming at recruiting 185 patients (NCT02665364)

For instance, Mardikian et al [69] reported the occurrence of some mild side-effects between 1200, 2400 and 3600 mg/day oral doses of NAC, lying in parallel with the findings of Berk et al [70,71] who evaluated a daily dose of 2 g of NAC (1000 mg twice daily) and also perceived some mild adverse effects

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