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Consequently, the mutation rate of mitochondrial DNA in the oocytes of women of advanced reproductive age increases, compromising the integrity of the mitochondrial ETC and precipitating oxidative stress within the oocytes (10)

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Ecotoxicity of irradiated solutions was assessed with use of Microtox bioassay

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However, we performed a drug safety evaluation, and ACE did not induce acute hepatic or renal injury or elevated ferrous ion levels in normal tissues