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Notably, it can potentially affect the efficacy or side-effect profile of drugs such as nitroglycerin, nitrates, and some chemotherapy agents

This functionalized GO served as a carrier for cellular delivery of oligohistidine- and biotin-tagged biomolecules such as proteins

Persistent or repeated exposure to non-biodegradable or slowly cleared nanomaterials may therefore shift an initially adaptive microglial response toward chronic neuroinflammation, synaptic dysfunction, and neurodegeneration, particularly in aged or disease-susceptible brains (169)

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