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Ferroptosis is increasingly implicated in a host of diseases, and unlike other cell death programs the physiological initiation of ferroptosis is conceived to occur not by an endogenous executioner, but by the withdrawal of cellular guardians that otherwise constantly oppose ferroptosis induction

doi: 10.1016/j.cell.2012.03.042 13 ZhouQMengYLiDYaoLLeJLiuYet al

Directing the lab studies toward applications in industry raises barriers such as involved extraction/purification techniques, expensive production methods and preclinical as well as clinical trials of considerable length ( 9.6 Limitations of current data and research methodology Despite the promising application prospects of PBPs in sports nutrition, the current body of evidence is constrained by several methodological limitations that require critical evaluation

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doi: 10.3389/fnins.2023.1211066