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For the most part, hypotheses related to these factors are not entirely new (113, 114, 126), but recent developments across several fields generate renewed interest (139)

[PubMed] Yin LK, Tong KS

Review of structure and bioactivity of the Plantago (Plantaginaceae) polysaccharides

However, the role of oxidative stress has only been proven for some types of cancer, neurodegenerative disorders (e.g., Alzheimers, Parkinsons, and Huntingtons disease), and conditions involving chronic inflammation (Halliwell, 2012