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Change history 16 April 2015 This article has been corrected since Online Publication and a corrigendum has also been published Abbreviations ACNU: nimustine BSO: buthionine sulfoximine CNU: chloroethylating nitrosourea CTR1: copper transport channel DSBs: double-strand breaks GSH: glutathione GST: glutathione S -transferase HCR: host-cell reactivation ICL: interstrand crosslink MGMT: O 6 -methylguanine-DNA methyltransferase NAC: N -acetyl cysteine NER: nucleotide excision repair (O 6 MeG): O 6 -methylguanine TMZ: temozolomide References Wen PY, Kesari S