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Psychiatry 21 925935

Thioredoxin regulates human mercaptopyruvate sulfurtransferase at physiologically relevant concentrations

Yen, Head of the Laboratory of Hormonal Regulation at Duke-NUS' Cardiovascular & Metabolic Disorders Programme, and senior author of the study, said, "The potential for using vitamin B12 and folate, which have high safety profiles and are designated as dietary supplements by the US Food and Drug Administration, as first-line therapies for the prevention and treatment of NASH could result in tremendous cost savings and reduce the health burden from NASH in both developed and developing countries." Professor Patrick Casey, Senior Vice-Dean for Research at Duke-NUS, said, "Currently, the only treatment for patients with end-stage liver disease is to receive a transplant