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Cell 160(12):177190 Liu C-C, Zhao N, Fu Y, Wang N, Linares C, Tsai C-W, Bu G (2017a) ApoE4 accelerates early seeding of amyloid pathology

4 Despite advancements in iPSC and organoid technology, as well as gene editing, developing accurate disease models continues to be a significant challenge, limiting research progress

528 CQ also modulates the expression and activity of the transcription factor Nurr1, which influences Treg differentiation, providing an additional mechanistic link between autophagy-related pathways and immune tolerance

Understanding the mechanisms of mitochondrial function in PD could aid the development of drugs targeted to preserve cell viability and monitor PD progression in patients 71