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When eliminating the lowest-quality article, heterogeneity ( I 2 = 35%, P = 0.22) was observed, and a meaningful difference was made between the two groups under random-effects evaluation (OR = 1.73, 95% CI: 1.482.01, Figure 2B)

Long-term epidemiological data exists for traditional tobacco oral products (snus) that demonstrate its Tobacco Harm Reduction potential

They have learned strategies to cope with the urge to smoke and they develop a sense of control and the ability to remain smoke-free

So, at its worst, chewing tobacco is twice the TSNA levels that snus has (Source: Brad Rodu)

Id much rather throw my body over a railing and flail