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This has led some health care providers to recommend the routine addition of a progestin to the estrogen therapy

Vitamin B 12 also facilitates energy production through food metabolism, supports healthy brain function, boosts the immune system, helps alleviate feelings of depression or anxiety, maintains the integrity of the central nervous system, promotes stable mood, and boosts the immune system

Notably, heatmap showing the expressions of significantly expressed genes from the pathways of interest was generated by the R package ggplot2 using the metric FPKM, and was colored by the z-score that was computed from the average FPKM of samples in each stage by subtracting the value of the average FPKM in the four stages then dividing by the standard deviation