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Description

Across all dosages, however, rotenone did not lead to oxidized HyPer7 in the IMS and OMM

Ketamine, generally, stimulates breathing

This conceptual integration is especially relevant in PD, in which hallmark features of oxytosis/ferroptosis including oxidative stress, iron accumulation, and glutathione depletionare prominently observed (Lewerenz et al., 2018)

Future investigations should harmonize outcome measures, longer monitoring periods, and integration of objective biomarkers (e.g., inflammatory or metabolic indices)