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A multi-center phase-II clinical trial, started a few years ago to investigate the biological and clinical effects of rapamycin in people with ALS, is currently underway and will provide important information for further potential trials [312], thus opening new therapeutic perspectives for ALS

Targeting ferroptosis against ischemia/reperfusion cardiac injury

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The cells were treated with increasing concentrations of NAC, with the dosage determined by the suppression of intracellular H 2 O 2 concentration and proliferation rate