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Importantly, dietary manipulations induce systemic responses that are not limited to the tumor itself and influence other stromal behaviors, such as the immune system and overall homeostasis

Treatment of Specific Cancers: Liposomal doxorubicin has been licensed for use in certain cancers, including breast cancer, ovarian cancer, and Kaposi's sarcoma

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Moreover, the efficacy of these drugs in MC4R KO mice aligns with clinical studies, indicating that MC4R KO mice serve as a reliable animal model for obesity research