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While TB-500 has intriguing animal data, as it stands, there are no standardized, evidence-based TB-500 dosage guidelines from large human studies

doi: 10.1016/j.arr.2023.102063 31 ConradMPrattDA

Renaldi et al., 2025)

Animals fed high fat or western diets consume more calories, but do not necessarily exhibit hyperphagia, whereas ob/ob animals consume more calories because of hyperphagia