Global, regional, and national liver cancer attributable to smoking and alcohol use burden, 19902021: analysis for the global burden of disease 2021 study
The generation of ROS plays the role of indirect damage to tumor cells, and this is observed in a large portion of DNA damage caused by low linear energy transfer radiation, such as X- and gamma-rays 13,14 Thus, ROS is an important factor in controlling tumor cell radio-resistance 15 To counteract ROS production and survive radiation therapy, radio-resistant tumor cells maintain increased levels of reductants, such as GSH, which protect cells from oxidative damage through reaction with electrophiles or ROS 6,16,17
It typically includes aerobic and resistance exercise, nutritional optimization, and sometimes mental health support (e.g., stress management or counseling)
J Immunol (2005) 174:315
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