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It is accepted that an excessive burden of ROS may lead to abnormal cell growth, corresponding changes in intracellular homeostasis and damage to important components of in the cell when the antioxidant defense and/or DNA repair mechanisms cannot balance the excess oxidants [29]

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doi: 10.1080/10428190500102555 158 NassNBrmmeH-JHartigRKorkmazSSelSHircheFet al

Nuclear pore and nucleocytoplasmic transport impairment in oxidative stress-induced neurodegeneration: relevance to molecular mechanisms in Pathogenesis of Parkinsons and other related neurodegenerative diseases

Effects of trace mineral deficiencies on cow production and reproduction Overall, TM deficiency impairs the immune response by affecting neutrophil and macrophage migration, phagocytic function, and killing activity, as well as the mechanisms of mucous membranes integrity