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Cell Mol Biol 66:185190

22 , 1827 (2020 Rajer, F., Allander, L., Karlsson, P

Table 1 Effects of Yang- and Qi-invigorating Chinese tonifying herbs on ATP-GC and reduced glutathione (GSH) levels in cultured H9c2 cardiomyocytes [modified from (9)] Full table On the other hand, Qi-invigorating herbal extracts were found not able to stimulate mitochondrial ATP-GC following a 4 h incubation, whereas all of them stimulated ATP-GC in H9c2 cells following incubation for 24 h ( Table 1 )

Likewise, treatment of aortic SMCs with IL-1 or IL-6 caused a dose-dependent increase in alkaline phosphatase activity and increased cell mineralization in vitro (196)

Conclusion: These promising findings advocate for the therapeutic potential of HepLPCs as an innovative strategy for liver cirrhosis, warranting further exploration through clinical trials, particularly in decompensated cirrhosis and acute-on-chronic liver failure patients