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The price differential reflects bioavailability differences, as nasal formulations require higher peptide quantities to achieve comparable effects

Materials and methods Ethic statements The animal studies were carried out in strict accordance with the Detailed Rules for the Administration of Animal Experiments for Medical Research Purposes issued by the Ministry of Health of the Peoples Republic of China and were approved by the Animal Experiment Administration Committee of The Fourth Military Medical University

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NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme studied in laboratory environments for its role in cellular energy metabolism, mitochondrial signaling, and longevity pathways