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They reported that AC could suppress HL-60 cell proliferation in a time- and concentration-dependent fashion, with a half-maximal inhibitory concentration (IC 50 ) of approximately 30 g/mL

All stakeholders are encouraged to consistently verify the registration status of food products and supplements by searching the brand, product name, and registration number (if available) of a product through the FDA Verification Portal accessible at

[DOI] [PubMed] [Google Scholar] 528

Prolonged metabolic stress impairs mitophagy and reduces mitochondrial function, as indicated by decreased oxidative phosphorylation, impaired ATP synthesis, and elevated reactive oxygen species (ROS) generation ( Hepatic lipid overload can also directly initiate inflammatory signaling by activating resident immune cells

Trimethylamine N-oxide promotes ApoE -/- mice atherosclerosis by inducing vascular endothelial cell pyroptosis via the SDHB/ROS pathway