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Plumbing Concerns: Conclusion It is important to maintain the pH level of drinking water between 6.5 and 8.5 to avoid negative impacts on human health and structures

NRF2 activity is also regulated by the availability of many binding partners, including a group of bZIP bi-directional transcription regulators named sMaf proteins (MafF, G and K) [200, 201] which, when bound to NRF2, under OS, favor its maintenance inside the nucleus thereby enhancing its activity [202]