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doi: 10.3390/toxics12050318

Ascorbic acid is a synthetic form of vitamin C

After 3 h of treatment, the most impacted pathways, revealed by 40 significantly changed metabolites, included amino acid metabolism (alanine, aspartate, and glutamate), the pentose phosphate pathway, the TCA cycle, purine metabolism, and pyrimidine metabolism (Figure 4A)

J Pharmacol Exp Ther 241:527533 Roberts DW, Bucci TJ, Benson RW, Warbritton AR, McRae TA, Pumford NR, Hinson JA (1991) Immunohistochemical localization and quantification of the 3-(Cystein- S -yl)-acetaminophen protein adduct in acetaminophen hepatotoxicity

The original 1977 Monnier study showed that dialysate from sleeping rabbit brains (containing DSIP) could induce delta-wave sleep when infused into waking rabbits