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[PMC free article] [PubMed] [Google Scholar] 18.Besse JL, Gadeyne S, Galand-Desm S, Lerat JL, Moyen B

The silencing of the Fmr1 gene and consequent lack of FMRP protein, is the major contribution to FXS pathophysiology

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The researchers observed increases in several markers commonly associated with early nerve-cell development and proposed that Epithalon may act partly through epigenetic interactions with chromatin-associated proteins

TABLE 1 Summary of genes and signaling pathways that play an important role in intervertebral disc development