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10.1038/nrm3013 52 WestermannB

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GSH conjugation begins with a reaction catalysed by glutathione-S-transferases (GSTs)

Animal models remain indispensable in preclinical evaluations, providing critical insights into the efficacy and safety of nanomaterials

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GSH can also regulate the expression of genes by modulating the redox state of proteins and transcription factors, but this mechanism is yet poorly understood (Dietz 2014