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What's your update after going back to see the doc

J Immunol Baltim Md 1950

Beyond metabolic regulation, peptides also modulate the immune system, impacting the development of chronic inflammatory diseases

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This browning is mediated through multiple pathways including SIRT1/PGC-1 activation, increased expression of thermogenic genes (UCP1, PRDM16, PPAR), and enhanced mitochondrial biogenesis