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Chemicals NNMT inhibitors and standards for LC/MS/MS studies were purchased from established commercial suppliers or synthesized in-house by established synthetic schemes as described previously.[17] SAM, NA, 1-MQ, 1,8-diMQ, NAD + , and 6-chloro nicotinamide (6-CN) were obtained from Sigma-Aldrich (St

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Czechia Greater than 99.8 % purity confirmed by COA Assay content verified at 55.1 mg Endotoxin level below 0.001 EU/mg No detectable heavy metals or microbial contamination NNMT-related research compound for controlled laboratory studies For research use only not for human or veterinary use For laboratory research only