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On January 4, 1927 The New York Times published an article notifying that Porto Rican-American Tobacco Co

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Cigarette smoke and histone posttranscriptional modifications Cigarette smoke and histone acetylation Previous studies reported that CS caused histone hyperacetylation in the lungs of both human smokers [29, 30], mouse models exposed to CS [31], and human bronchial epithelial (HBE) cells treated with cigarette smoke extract (CSE) in vitro [32]

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