L.SibilanoR.WatzenboeckM
A 43-amino acid synthetic peptide modeled after thymosin beta-4.- Reported to regulate actin dynamics via its LKKTETQ sequence, thereby influencing cellular migration and motility.- May also elevate microRNA-146a, which suppresses inflammatory pathways involving IRAK1 and TRAF6.- Preclinical studies point toward roles in wound contraction, tissue vascularization, and cardiac resilience under stress
Poster Session II - RISK FACTORS - PRIMARY AND SECONDAR PREVENTION 05.00 - RISK FACTORS AND PREVENTION (PRIMARY AND SECONDARY) - 05.03 - EPIDEMIOLOGY & RISK FACTORS P990 - ESOC25-1846 SLEEP DEEPER: INVESTIGATING THE LINK BETWEEN SLEEP QUALITY AND CEREBRAL SMALL VESSEL DISEASE Mareike Ludwig 1 , Arne Bttcher 2 , Hoffmann Anna-Sophie 2 , Marvin Petersen 1 , Clausen Jacob Friedrich 2 , Gtz Thomalla, Ines Schfer 3 , Alena Haack 3 , Betz Christian 2 , Bastian Cheng 1 1 Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 2 Department of Otorhinolaryngology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 3 Epidemiological Study Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany Background and Aims: Increasing evidence links sleep quality to cerebral small vessel disease (CSVD), which may contribute to vascular dementia
Aberrant vasculature resulting from tumor angiogenesis plays a critical role in the development of resistance to breast cancer treatments, via exacerbation of tumor hypoxia, decreased effective drug concentrations within tumors, and immune-related mechanisms
Introduction The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in early 2020 led to hundreds of millions of confirmed infections and a substantial global mortality burden
