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MTHFR-impaired SAMe limits COMT below its Val158Met genotypic capacity

doi: 10.19540/j.cnki.cjcmm.20190129.001

[Abstract]2024 Jun 25:1243:124210

Oleanolic acid inhibits increased cellular and mitochondrial ROS production in obese diabetic db/db mice and the authors speculate that Nrf2GCLc-mediated stabilization of mitochondrial GSH pool may be involved in the protective actions of oleanolic acid [118]