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Weeks 5 through 12: acceleration phase As the dose increases and appetite suppression intensifies, the risk of under-eating becomes real

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Introduction The concept of the leaky gut also known as increased intestinal permeability has been described many years ago and is currently receiving increasing attention in the scientific literature but also in the media because of its proposed associations with numerous conditions that do not necessarily affect the gastrointestinal (GI) tract, such as asthma, Alzheimer's disease, diabetes among others

First, more molecular and cellular mechanisms through which the circadian rhythm regulates tissue deterioration need to be explored