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Such an effect resulted in an unstable expansion of the nanoprobe and ultimately led to its violent collapse, which caused rapid drug release 32

Clin Pharmacol Ther 81(5):692698 Ricke KM et al (2020) Mitochondrial dysfunction combined with high calcium load leads to impaired antioxidant defense underlying the selective loss of nigral dopaminergic neurons

10.1074/jbc.M509973200 157 GuillotT

46 AAV vectors are derived from the non-pathogenic parvovirus, AAV, which has the advantage of minimally integrating into the host genome, thereby reducing the risk of insertional mutagenesis