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In one of our studies, we discovered that T cells with TCRs that poorly activate NF-B signalingdue to defects in forming the CBM complexare unable to differentiate into circulating memory CD8 T cells during a systemic bacterial infection, despite normal effector differentiation (161)

The first approved antiretroviral drug was zidovudine (AZT), a nucleoside reverse transcriptase inhibitor

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The development of editing techniques such as Meshcher-Garwood point resolved spectroscopy (MEGA-PRESS) to effectively suppress nearby resonance peaks of other neurochemicals (e.g., Cr: 3.03 p.p.m