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50 (43%) PTB patients were smokers, double the reported incidence in the general adult population ( p = 0.004 and p = 0.0004, regarding 2000 and 2010, respectively), and 1.5 times higher than the incidence of the reference population (cohort 1) ( p = 0.02)

Germany, China, the United Arab Emirates and South Korea lagged somewhat behind, together comprising a further 13%

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These findings are in agreement with a prior study that showed daily use versus non-daily use and attempts to stop e-cigarette use to be associated with dependence levels 31