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The FDA designates curcumin as Generally Recognized As Safe (GRAS) for use as a food additive

10.1038/s41588-020-00753-3 145 NtermaP.PanopoulouE.Papadaki-PetrouE.AssimakopoulouM

Moreover, the inhibition of electron transport chains by exosomes significantly increases the reductive carboxylation of glutamine biosynthesis in cancer cells [328]