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Evidence of a key role of inflammation in fetal programming was provided by Reynolds et al

Targeting at lipogenesis, pyruvate carboxylase is proven to activate AKT/mTOR pathway, thus upregulating SREBP1c and FASN-induced lipogenesis in TC cells, which promotes anticancer effects [128]

Steenbergen L, Sellaro R, van Hemert S, Bosch JA, Colzato LS (2015) A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood