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Given the lack of rare missense variants that have been annotated as likely benign or benign in ClinVar, we instead used gnomAD variants (after excluding known or suspected pathogenic variants) as a negative reference set

[DOI] [PubMed] [Google Scholar] 15.Gey KF

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doi: 10.3390/microorganisms11040991 112 VidalMSJr.LintaoRCVSeverinoMELTantengcoOAGMenonR

10 Persistent NF-B activation drives inflammaging, which impairs immune surveillance, reduces T cell diversity, and promotes tissue degeneration