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Brain Sci 13(2):345

Exercise did not cause a significant change in the GK rat kidneys

This event may represent a possible mechanism by which myelin phagocytosis results in a pro-inflammatory response and would explain the acquisition of the inflammatory role of microglia in later stages of the lesion

Mitochondria contain multiple copies of their own genome, mitochondrial DNA (mtDNA), which encodes for 13 polypeptides of the OXPHOS and respiratory chain, as well as two ribosomal RNAs and 22 transfer RNAs necessary for translation of polypeptides inside mitochondria