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6 d, e)

Increased glycine and serine concentrations may be the result from the reduced activity of these enzymes

doi: 10.1186/s13045-022-01313-4

Late-onset AD can result in the presence of the 4 allele of the apolipoprotein E (APOE-4) gene (148, 161, 252, 323325) ( Figure 1 )

The increase in the secreted IL-17F level results in the unregulated expression of protumor genes and the induced inflammatory responses, ultimately accelerating the proliferation, migration and invasion of breast tumors