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Furthermore, actively cycling CAR T cells isolated from a patient with a decade-long leukemia remission showed upregulation in LDHA and OXPHOS pathways, suggesting that both aerobic glycolysis and mitochondrial respiration are increased in CAR T cells that persist long-term 25

Liang Y, Zheng T, Song R, Wang J, Yin D, Wang L, et al

Relation of alcohol consumption and coronary heart disease in hypertensive male physicians (from the Physicians Health Study)

Carotenoids are incredibly powerful antioxidants and are known as the most potent physical quencher of singlet oxygen [164]

Metabolic and endocrine factors are also at play