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Figure 1 Beyond canonical fusion-driven settings, preclinical work indicates that NGFTrkA signaling can be pharmacologically suppressed to blunt prometastatic programmes even in fusion-negative osteosarcoma

Although all NSAIDs and ASA are known to inhibit COX-2, only ibuprofen was shown to have some impact on PD prevention

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While it's an exciting discovery, these three time-tested recommendations are still important