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382 Moreover, they reported that the expression of BCL-2 in CD8 + T cells was correlated with the exhausted phenotype (CD8 + PD-1 + Tim-3 + ), and impaired cell cytotoxicity manifested as low expression of granzyme B and perforin, 382 which was consistent with the previous finding reported by Mathew et al

Vitamin C supplements can also be used to help increase the levels of vitamin C in the body