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In low-price countries, small to moderate increases in price had relatively little effect on bootlegging, but the simulation suggested that bootlegging may be a problem in relatively high-price countries if increases in cigarette taxes and policies are not coordinated

In one characteristic study, published in 2022 in the American Journal of Gastroenterology , researchers compared admissions for CHS at a large Massachusetts hospital between 2012 and 2020, noting a significant uptick after cannabis was legalized in the state in late 2016

This measures consecutive excitement, tracking the biological and psychological rush people feel when they obtain something they want

The authors also thank Susie Davenport and Laurel Tully of British American Tobacco (Cambridge, U.K.) for generation of plant materials for genome and transcriptome studies

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