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Finally, the longest (28-day) Phase I study with BMS-830216, a pharmacological antagonist of MCH signaling (36) produced no indications of weight loss or reduced food intake and the compound did not proceed to Phase II studies

9,16 Despite huge advances in our understanding of endometriosis, knowledge of the epidemiology and symptomatology of endometrioma compared to deep infiltrating endometriosis is considered rudimentary, leading to controversy about the epidemiology and development of these phenotypes