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However, under conditions of selenium deficiency, germ-free mice exhibited elevated glutathione peroxidase (GPx) and thioredoxin reductase (TrxR) activities in the gut and liver, along with higher selenium levels in plasma and liver tissues 46

Myeloid cells may also incite local fibrosis-mediated tissue injury and sustain proinflammatory cytokine levels contributing to the clinical development of PASC

This information, along with data on plasma ascorbate concentrations achievable in humans intravenously, allows us to set a recommended target dose per infusion

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