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Indeed, GLS inhibitors have shown promising tumor-suppressive activities in preclinical models for 968 and bis-2-(5-phenylacetamido-1,3,4-thiadiazol-2-yl)ethyl sulfide (BPTES), or even in clinical models for CB-839 [100,101]

high expression levels are predictive of poor clinical outcome 1

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[DOI] [PMC free article] [PubMed] [Google Scholar] Kang, M