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[DOI] [PubMed] [Google Scholar] 133.Gladyshev VN, Liu A, Novoselov SV, Krysan K, Sun QA, Kryukov VM, Kryukov GV, Lou MF

The oxidized form of glutathione (glutathione disulfide), which is generated during the reduction of hydroperoxides by GPX4, is recycled by glutathione reductase and NADPH/H +

190 In mammals, the sirtuin family comprises seven proteins (SIRT1SIRT7), each with distinct tissue specificity, subcellular localization, enzymatic activity, and target genes

111,112 This was achieved through the activation of the Nrf2 pathway, increased GSH levels, decreased inflammatory factors, and subsequently enhanced recovery