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Critical considerations for bodybuilders Muscle loss: GLP-1-class compounds can cause muscle loss if sufficient protein is not consumed (~2 g per kg body weight) and resistance training is not performed

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The element quantitative analysis of samples was conducted on inductively coupled plasma-optical emission spectrometry (ICP-OES, Agilent 725, Agilent Technologies, US)

Individual selenoproteins can regulate the redox state and the activity of transcription factors: nuclear factor B (NF-B) and activator protein 1 (AP-1) [57, 60], which are sensitive to oxidative processes

Freezing can cause protein aggregation in the semaglutide component and may damage the physical structure of the solution, potentially leading to particulate formation or changes in drug concentration