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HIF-1 may improve UC by regulating the transcription of GPX4 to inhibit ferroptosis in IECs

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Previous studies have stated that pyrogenic cytokines can induce the production of COX-2 and mPGES-1 through various signaling pathways, so the PGE2 produced by brain endothelial cells is primarily mediated by the effect of these pyrogenic cytokines

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