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Similarly, Almadaly et al

Ferroptosis is also regulated by the FSP1-CoQ10 axis, with FSP1 serving as a CoQ1 oxidoreductase

Vitamin B12 also interacts closely with neurotransmitters within the brain and appears beneficial in Autism

Although numerous preclinical studies have shown that iron chelators such as deferoxamine (DFO), deferiprone (DFP), and PBT2 effectively mitigate brain iron overload, reduce amyloid burden, and improve cognition in AD models, translation to the clinic has proven challenging

Int J Mol Med 31(1):265271 Del Campo-Rota IM, Delgado-Casillas OM, Ibarra A (2024) Cognitive impairment induced by gestational diabetes: implications of oxidative stress as an inducing mechanism