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We mark 250 years since the signing of the Declaration of Independence, what Jefferson scholars have called the document containing the greatest sentence ever written: 1 We hold these truths to be self-evident, that all men are created equal, that they are endowed by their Creator with certain unalienable Rights, that among these are Life, Liberty and the pursuit of Happiness. 2 But we celebrate under ominous clouds

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Recombinant lentivirus was produced using transient 293T cell transfection