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10.1002/eji.201142361 53 GongN.ZhangY.ZhangZ.LiX.LiangX

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Oxidative stress occurs when ROS, such as those derived from hydrogen peroxide (H 2 O 2 ), exceed the physiological levels required for normal redox reactions and cell signalling

Moreover, penile growth involved not only androgen-dependent processes but also some independent procedures 17,19,55 that 6/13 individual steps for human penile development and 5/11 for mice were reported to be androgen-independent 55 , while these nonandrogenic hormones like thyroxin, glucocorticoids or growth hormone might not be corrected simply by testosterone administration 56